CLINICAL EFFICACY OF NEBULIZED DEXMEDETOMIDINE IN CONSCIOUS SEDATION IN DAY CARE FLEXIBLE BRONCHOSCOPE
Keywords:
Bronchoscopy,, Conscious sedation,, nebulized dexmedetomidine,, , flexible bronchoscopyAbstract
ackground: Sedative agents used in bronchoscopy procedures need trained professional personnel for administration and
monitor the subjects. The increase in the cost of procedure, inpatient stay, and duration. Inhalational use of sedative agents
can be a practical solution to the issue. Dexmedetomidine in the inhalational form can be given results similar to the
intravenous form with no significant adverse events.
Aim: The present study aimed to assess the clinical efficacy of nebulized dexmedetomidine in conscious sedation in
daycare flexible bronchoscopy.
Methods: The present study prospectively assessed subjects that needed bronchoscopy and these subjects were randomized
to attain the nebulized form of either 0.9% saline or dexmedetomidine before bronchoscopy. The study parameters were
recorded and assessed before, during, and following bronchoscopy. Data gathered were analysed statistically for results
formulation.
Results: The study results showed that side effects are minimized using commonly given sedation agents in bronchoscopy
including dexmedetomidine, fentanyl, and midazolam. The nebulized dexmedetomidine is a safe and efficacious agent for
sedation compared to a placebo. Conscious sedation administration decreases inpatient stay and cost. Exhaustion of
hemodynamic parameters by dexmedetomidine can be advantageous in reducing unwanted effects.
Conclusions: The present study concludes that dexmedetomidine in a nebulized form improves the comfort of subjects
during the procedure. It decreases the pressure response during bronchoscopy and can be a cost-effective and safer agent in
nebulized form for conscious sedation in bronchoscopy.