ANTHELMINTIC ACTIVITY OF TECTONA GRANDIS LINN FRUITS

Abstract

The objective of the present work was to evaluate the anthelmintic property of ethanolic extract of Tecona grandis fruits using Indian earthworm Pheretima posthuma as test worm. Various concentrations of ethanolic extract were tested in bioassay which involved determination of time of paralysis (P) and time of death (D) of the worm. Piperazine citrate (10mg/ml) was used as reference standard. The result of present study indicates that the crude ethanolic extract significantly demonstrated paralysis, and also caused death of worms especially at higher concentration (50 mg/ml) compared to standard reference Piperazine citrate. To conclude, the use of the fruits of Tectona grandis as anthelmintic has been confirmed and further studies are suggested to isolate the active principles responsible for the activity.