GAS CHROMATOGRAPHY AND MASS SPECTROSCOPY ANALYSIS OF BIOACTIVE COMPOUNDS OF ADIANTUM LATIFOLIUM LAM.

Abstract

Adiantum latifolium Lam. is an important medicinal fern belongs to the family Adiantaceae. The medicinal property of Adiantum latifolium is yet to explore except a few secondary metabolites on quantitative analysis level. The present study is the maiden effort and aims at analyzing Gas Chromatography and Mass Spectroscopy analysis of whole plant Ethanolic extract of Adiantum latifolium Lam. The study was carried out with GC- MS instrument of ITQ 900 Model of Thermo Fisher Scientific make. The Ethanolic plants samples revealed fifteen bioactive compounds, through GC- MS such as 1:Propane, 1,1- diethoxy- (8.30%), 2:Benzoic acid, 3-diethylamino-, ethylester (14.67%).3: Diethylpyridine-3,4-dicarboxylate (15.71%). 4:(5R,8aR)-5-PropyloctahydroIndolizine(18.26%), 5:2Hexyldecanoicacid(19.90%), 6:Ecosen-1-ol,cis-9-(21.24%), 7:12-hydroxy-14-methyl- oxacyclotetradec6en2one(21.72%),8:Pregnane 3, 20dione,17,21[(methylborylene)bis(oxy)]-, (5a) (21.92%), 9:Stigmastanol (23.64%), 10:12 Hydroxyabieta-8,11,13-triene6,7-dione(23.14%), 11: Androst-5-en-3-one, 19-acetoxy4, 4di methyl ,oxime(24.84%), 12: Pyrrolo[3,2-k]anthracene-4,6- diole,(25.82%), 13: Isotetrahydrohis trotoxin287a(26.92%),14:Cephalotaxin(31.48%), 15:8,9-Seco-3,19-epoxyandrostane-8,9 dione, 17-acetoxy- 3methoxy-4,4-dimethyl-(33.70%). Based on the references the identified compounds were found to be antioxidant, antimicrobial and anti-infective agent. Some of the compounds seem to possess therapeutic agents for primary treatment for HIV/AIDS etc. Anticancer compound is also reported. Moreover, compounds with unknown activity were also reported. Hence the present experimental plant possess compounds with different curative properties. The further analysis for photochemical for therapeutic molecule from this plant is continued.