DEVELOPMENT OF SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF BACLOFEN DRUG

Authors

  • Marwa S. Falih, Ruba F. Abbas
  • M. Hussain Arwa
  • M. Hammed Wejdan
  • A. Abdul abass Dhifaf

Keywords:

Baclofen, Area under curve, First and Second derivative Spectrophotometric.

Abstract

Accurate, direct and inexpensive spectrophotometric methods have been used for simultaneous estimation of Baclofen in bulk and tablet dosage form. The proposed methods were applied in the wide concentration ranges of (50–450 mg/L). The detection limits were (0.451) for AUC1 and (0.520) for AUC2. The limit of quantitation was found to be (1.366) for AUC1 and (1.576) for AUC2. The results were analyzed statistically by using recovery and relative standard deviation studies.

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Published

12-11-2018