EFFICACY OF SOLANUM TORVUM (BERRIES) ON CARRAGEENAN INDUCED RAT PAW EDEMA MODEL AN IN-VIVO ANTI-INFLAMMATORY STUDY

Abstract

Solanum torvum, commonly called as Hativekuri, is very popular as an anti-inflammatory medicine among the Tiwa communities of Morigaon district Assam, India. The methanolic extract of the raw berries of Solanum torvum was investigated for its anti inflammatory activity in animal model. The extract at different doses (300 and 600 mg/kg b.w.) used showed good anti inflammatory activity which has been done significantly, by the formation of edema induced by carrageenan. These results were also comparable to indomethacene, the reference drugs used in this study. The results from present study indicate the efficacy of the methanolic extract as a therapeutic agent in acute as well as chronic inflammatory properties. The phytochemical screening revealed the presence of active phytoconstituents i.e. flavonoids and phenolics, which may offer anti-inflammatory conditions. Thus it could be concluded that the methanolic extract of raw berries of Solanum torvum possess significant anti-inflammatory properties.