ANTIBACTERIAL ACTIVITY OF ZALEYA GOVINDIA AGAINST SOME PATHOGENIC MICROBES OF NORTHERN RAJASTHAN, INDIA

Abstract

The in vitro antimicrobial activity of crude ethanolic extracts of the plant parts (leaf, root & stem) of Zaleya govindia was investigated. For antibacterial activities test, the extracts were subjected to its effectiveness against both Gram (+ve) and Gram (-ve) bacteria in disk diffusion method. The opportunistic bacterial strains are Escherichia coli, Pseudomonas aerunginosa, Streptococcus pyogenes, Shigella dysentriae, Vibrio cholerae, Bacillus subtilis, Salmonella typhi, Staphylococcus aureus, Klebsiella pneumoniae & Agrobacterium rhizogenes. The zones of inhibition produced by the crude ethanol extracts against few sensitive strains were measured and compared with those of standard antibiotics Streptomycin, Ampicillin, Gentamycin & Tetracycline. The extracts produced greatest inhibitory zone on S. aureus one of the major wound infectious bacterial strain. The obtained results provide a support for the use of this plant in traditional medicine as in conjunctivitis, menstrual regulation in female and to prevent wound infections suggest its further investigation.