COMPREHENSIVE REVIEW ON EUDRAGIT POLYMERS

Authors

  • Amrish Chandra
  • Abhijit Sonje

Keywords:

Physicochemical properties, Eudragit, Controlled release, Polymers, Pulsatile drug delivery system

Abstract

For ideal Pulsatile drug delivery system, dosage form should possess three main properties: (a) It will be a single dose for the whole duration of treatment. (b) It will deliver the active drug directly at the site of action. (c) It will possess possible fewer side effects. Above approaches are achieved with the help of suitable choice of polymer. Release rate of drug from the formulation and duration depend on selection of polymer. One would always like to have an ideal polymer for controlled release of drug from particular dosage form that must possess the following two properties. 1) Polymer stability in acidic environment with desired buoyancy. 2) It should dissolve slowly enough to serve predictable release rate. This review focuses on recent literature regarding use of Eudragit polymer in different drug delivery systems with special attention to used in its fabrication along with their physiochemical properties. Collected data of polymers will provide a deep and current knowledge for further researchers to conduct study regarding Pulsatile drug delivery system.

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Published

11-05-2013