AN UPDATE ON PHARMACOLOGICAL PROPERTIES OF RESVERATROL

Authors

  • Agnihotri Gaytri
  • Sharma Ramica
  • Rana A C

Keywords:

resveratrol, ischemic reperfusion, antioxidant, inflammation

Abstract

 

Resveratrol, red wine mainly present in grapes acts as a natural phytoalexin and phytoestrogen. It has potent antioxidant activity and then has been implicated in the management of various cardiovascular and inflammatory disorders. Further, it has been also documented to be successful in the reduction of ischemic reperfusion [I/R] injury. It has been found to possess immunosuppressive property and is used as anti-cancer and ameliorates the endothelial functions. Still, no evidence is availible that suggest signaling pathway mechanism associated with resveratrol. Thus, the present review deals with the update of various signaling pathway and therapeutic implications of resveratrol in the management of various disorders.

 

 

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Published

10-07-2012