EFFICACY OF HISTOPATHOLOGY TO TVS/TAS IN DIAGNOSING THE ABNORMAL UTERINE BLEEDING: A PROSPECTIVE CLINICAL STUDY

Abstract

Background: Abnormal Uterine Bleeding (AUB) refers to any bleeding that deviates from normal in terms of volume, frequency, regularity, and duration. Menorrhagia, polymenorrhea, metorrhagia, and oligomenorrhea are some      of      the      words      used      to       describe       abnormal       bleeding       during       menstruation. Aim: The current clinical study's goals were to evaluate the effectiveness of TVS/TAS and histopathological results in individuals with AUB.

Methods: 102 participants with abnormal uterine bleeding between the ages of 21 and 85 made up this prospective clinical trial. In spite of baseline examinations and sonography results, all subjects received hysteroscopy, premenstrual dilatation, and curettage. Histological analysis was used to evaluate the acquired endometrial tissue.

Results: The findings indicate that 3.92% (n=4), 12.74% (n=13), 2.94% (n=3), 32.35% (n=33), 51.96% (n=53), and 54.90% (n=56) of the study participants had cervical carcinoma, endometrial carcinoma, cervical polyp, endometrial polyp, adenomyosis, and myoma, respectively. The study's tissue findings were categorized as follows: 1.96% (n=2), 10.78% (n=11), 5.88% (n=6), 0.98% (n=1), 2.94% (n=3), 3.92% (n=4), 15.68% (n=16),

11.76% (n=12), 25.49% (n=26), and 20.58% (n=21) subjects had cervical cancer, endometrial cancer, endometrial polyp, endometritis, atrophic endometrium, mixed, secretary, proliferative phase, endometrial hyperplasia, and normal epithelium, respectively.

Conclusion: The current study concludes that transvaginal/transabdominal ultrasounds should be a regular part of assessment and examination procedures since they are a cost-effective primary assessment tool for the detection of AUB. Histopathologic examination is the gold standard in cases of non-gravid females with AUB, despite the fact that the diagnosis and treatment of the condition might be complicated.