AN EXPLORATION OF SUNDRY NATURE OF BENZOTRIAZOLE DERIVATIVES: A REVIEW

Abstract

Benzotriazole has been a matter of discussion among scientific community due to its potential characteristics and touched areas such as medicinal, pharmacological, clinical, industrial etc. On screening the literature, this work for the first time gave a comprehensive review on the latest and remarkable developments of benzotriazole derivatives covering multifarious number of activities such as antifungal, antibacterial, anticancer, anthelmintic, antidepressant, antioxidative, antitubercular, antiviral, anticorrosive, plant growth inhibitor, anti-inflammatory, etc. The purpose of this study was to explore its sundry nature, to investigate the most active site and to generate a data base for prominent methods of synthesis for benzotriazole derivatives in a single review article which has not been done before. The investigation through this review article has revealed that, the credit for sundry nature of benzotriazole derivatives goes to 1-position nitrogen in benzotriazoles. The study has put a light on the fact that, when various substituents are added to 1-position nitrogen in benzotriazoles it effectively contributes toward its diverse nature.