STUDIES ON PHYSICOCHEMICAL PARAMETERS, QUANTIFICATION OF PHYTOCONSTITUENTS AND IN VITRO ANTIOXIDANT STUDY OF Myxopyrum SPECIES

Abstract

Objective: The present study objective is to carry out physicochemical parameters, quantification of secondary metabolites and in vitro antioxidant activity of Myxopyrum serratulum A.W Hill. Methods: Powdered drug was subjected to physicochemical analysis. The various extracts were subjected to carry out Quantification of secondary metabolites by standard procedure and invitro scavenging assay by DPPH method and nitric oxide assay of selected medicinal plant. Results: Quantification of secondary metabolites indicates the higher percentage of flavonoids, phenols, tannins in ethanol when compared to other solvent extracts. Invitro antioxidant by DPPH method showed significant activity with % inhibition as 78.19% at 1000 µg/ml and Nitric oxide showed significant activity with% inhibition as 75.84% 1000 µg/ml. Conclusion: The present investigation of invitro antioxidant activity proved to exhibit significant activity which is comparable against standard drug vitamin C.