EVALUATING THE EFFECTS ON HEMATOLOGIC PARAMETERS BY FREQUENT PLATELET PHERESIS DONATIONS
Keywords:
Mean Corpuscular HB Concentration (MCHC), Mean Corpuscular HB (MCH), Plateletpheresis, Single Donor Platelets, White Blood Cells (WBC)Abstract
Background: Platelet components are prepared from either whole-blood donation or apheresis collection. Subjects who
donate platelets often are the focus of more concern.
Aim: The purpose of this study was to evaluate how frequent plateletpheresis affected the hematologic parameters in the
donors who were doing it often.
Methods: Participants in the current study were plateletpheresis donors who had donated twice in a month. Additionally,
donors having platelet pheresis for the third or fourth time had to meet the inclusion criteria. After platelet pheresis, the
hematologic parameters were evaluated and compared on recalls.
Results: There was a non-significant difference in all the parameters between the two study subject groups' pre-first and
pre-second durations, with the exception of haemoglobin, for which the intergroup p-values were 0.227 and 0.882 for
PDW, 0.886 and 0.368 for MOV, 0.459 and 0.084 for PCT, 0.279 and 0.004 for TPC, and 0.376 and 0.438 for TLC,
0.487 and 0.333 for RDW, 0.236 and 0.434 for MCHC, 0.209 and 0.047 for MCH, 0.077 and 0.100 for MCV, 0.416 and
0.867 for HCT, 0.025 and 0.029 for RBC, and 0.285 and 0.604 for haemoglobin, respectively. The intragroup difference
was not statistically significant across all measures.
Conclusion: According to the current study's findings, plateletpheresis may be performed often on these donors without
negatively affecting their hematologic parameters. Same follow-up findings post-donation were found for hematologic
parameters in the donors.
