ANALYZING THE RELATIONSHIP BETWEEN MEAN PLATELET VOLUME AND LIPID PROFILE INCLUDING TRIGLYCERIDES, VLDL, HDL, LDL AND TOTAL CHOLESTEROL TO MEAN PLATELET VOLUME

Abstract

Background: The average platelet size is evaluated by Mean Platelet Volume (MPV), which is a crucial component in
the evaluation of atherosclerosis. Clot retraction, procoagulant activity, secretion, aggregation, shape change and
spreading, and adhesion are among the activities of platelets. Electrical impedance can be used by the ABX Pentra
automated analyzer to assess MPV. Atherosclerosis is predicted by cholesterol levels.
Aim: The goal of the current study was to determine how mean platelet volume and lipid profile markers, such as
triglycerides, VLDL, HDL, LDL, and total cholesterol, correlated.
Methods: The link between lipid profile indicators, such as triglycerides, VLDL, HDL, LDL, and total cholesterol, and
mean platelet volume was examined in 48 research participants who had no history of platelet dysfunction, alcohol use,
or medication-induced platelet decline
Results: The study's findings indicate that mean platelet volume and HDL had an unfavourable relationship. Therefore,
the techniques used to raise HDL will result in a lower MPV and a lower risk of atherosclerosis. Additionally, there was
a positive but statistically insignificant connection between VLDL and MPV and triglycerides. There was an observed
negative and non-significant association between MPV and total cholesterol and LDL