UV VISIBLE SPECTROPHOTOMETRIC ESTIMATION OF GANCICLOVIR

Abstract

A low cost precise, accurate and more economical spectrophotometric method has been developed for the estimation of Ganciclovir in bulk and tablet dosage form. Ganciclovir shows maximum absorbance at 420nm in presence of solvent chloroform ,double distilled water and phosphate buffer of pH
7.4. The Beer’s law is obeyed in the concentration range of 2-16 $\mu$g/ mL and the graph shows a straight line with correlation coefficient of 0 .9970. The assay method of the drug was validated by accuracy and precision of the proposed method. The results are validated as per the directions of International conference on Harmonization.