GC-MS ANALYSIS OF CHEMICAL CONSTITUENTS IN THE METHANOLIC TUBER EXTRACT OF MOMORDICA CYMBALARIA Hook. F.

Abstract

The plant Momordica cymbalaria belongs to the family Cucurbitaceae. The Momordica genus found in the Indian states of Andhra, Karnataka, Madhya Pradesh, Maharashtra and Tamil Nadu. The plant is traditionally used for the treatment of diabetes mellitus, reumatism, ulcer, skin disease and diarrhea. It is used in the local folk medicine as an abortifacient and for the treatments of diabetes mellitus. In the present study, the powdered tuber of M. cymbalaria was successively extracted with Methanol through soxhlet apparatus. The GC-MS analysis has shown the presence of different chemical constituents in the methanolic tuber extract of M. cymbalaria. A total of 23 chemical constituents were identified in the methanolic tuber extract of M. cymbalaria. At (16.98) retention time 2,4,6-Cycloheptatrien-1-one, 3,5-bis-trimeth, Tetrasiloxane, decamethyl, and Methyltris (trimethylsiloxy) silane compound were found to be high (11.17%) and the lowest percentage (1.88%) was found to be Trimethyl (4-tert-butylphenoxy) silane, Silicic acid, diethyl bis (trimethylsilyl) ester and Cyclotrisiloxane, hexamethyl. The present study enhances the traditional usage of tuber of M. cymbalaria which possess many chemical constituents it can be used for the treatment of various diseases.