A COMPREHENSIVE STANDARDIZATION STUDY OF A POLY HERBAL FORMULATION: URAL TABLET

Abstract

More than half the world’s population is dependent on herbal drugs and in order to enter into the global market it is vital to maintain the quality. Initially the crude drugs were identified by comparison only with the standard description available. At present due to advancement in the chemical knowledge of crude drugs various methods like botanical, chemical and biological methods are being used for estimating active constituents present in the crude drugs in addition to its physical constants. According to pharmaceutical manufacturers association of U.S. quality is the sum of all the factors which contribute directly or indirectly to the safety, effectiveness and acceptability of the product. In this research work, a polyherbal formulation (PHF), Ural Tablet has been taken to establish its standardization level using various physic chemical parameters such as pH, Moisture content, ash values, HPTLC fingerprinting and assays of marker compounds with the aid of sophisticated instruments and was carried out to check the presence of the raw materials in comparison with the finished product. Study results revealed that product was well standardized at selected analytical parameters. All the tests were carried out in triplicates after which their SD was calculated. All the raw materials as well as finished product were found free from heavy metal and microbial contaminants.