EVALUATION OF HIBISCUS CANNABINUS SEED MUCILAGE AS A TABLET BINDER

Abstract

The present study was performed with an objective to find out the potentials of mucilage extracted from plant Hibiscus cannabinus as a tablet binder. The mucilage was extracted by using water as solvent and precipitated using ethanol as non-solvent. Physical characteristics such as solubility, swelling index, loss on drying, and pH of mucilage were studied. Paracetamol (Crocin) was used as model drug for formulation of tablet. Different batches of tablets with concentration of mucilage ranging from 1 to 10% were formulated. The evaluation parameters such as Hardness, dissolution time, Disintegration time, pH, were studied. The tablets prepared with 4% of mucilage were found to be ideal and comparable with a commercial marketed preparation Crocin.