ANALGESIC POTENTIAL OF THE ROOTS OF MEMECYLON UMBELLATUM (Burm)

Abstract

The ethanol extract of Memecylon umbellatum roots (EMUR) was investigated for analgesic activity for its central and peripheral analgesic activity in tail-flick, hot plate and acetic acid induced writhing models respectively. The EMUR at a dose of 100, 200, 400 mg/kg body weight showed significant and dose dependent analgesic activity in all animal models. The plant extract (EMUR) showed more prominent peripheral effect than the Central effect. The analgesic activity may be attributed to the presence of flavonoides and other phenolic compounds. The findings further suggest that the plant is good candidate for further investigation in other models of inflammations.