PHARMACEUTICAL MODIFICATION OF KUSHTADI CHURNA INTO TOOTHPASTE FORM

Abstract

Kushtadi Churna is one of the classical formulations described in Chakradatta, Mukharoga adhikara which is used for problems related to tooth and gums. There is no research work has been carried out on the standardization and quality control aspects of Kushtadi Churna. In the present study, an attempt was made to prepare an elegant Toothpaste, from the already explained formulations in classics for pratisarana i.e. Kushtadichurna. It consists of two broad heading as- Pharmaceutical study and Analytical study. Detail description of the manufacturing process of Kushtadi Churna and its modified dosage form i.e. Kushtadi Toothpaste is prepared and pharmaceutical observations like duration, specific finding and yield obtained after the process etc. were recorded. After performing many trials and errors, a final composition of kushtadi toothpaste, which had good aroma, acceptable taste, elegancy and the criteria which was eligible for toothpaste formulation was made final for the rest of the study. The analytical study was carried out for both kushtadi churna and its toothpaste. The evaluation criteria for toothpaste were done and the HPTLC study, Anti-microbial study as well as Culture Sensitivity Test, in which the toothpaste has given a good result. Therefore in consideration with the results obtained, it is seen that there is much difference in Pharmaceutical and Analytical study of Kushtadi Churna and its tooth paste and therefore both are having a good efficacy on oral bacteria’s considering the results obtained after the analytical studies.