HEPATOPROTECTIVE EFFECT OF INDIGOFERA LINNAEI ALI. ON CARBON TETRACHLORIDE INDUCED WISTAR ALBINO RATS

Abstract

The present investigation has been carried out the hepatoprotective activity of Indigofera linnaei Ali on carbon tetrachloride induced wistar albino rats. Carbon tetrachloride induced liver damage was well manifested by significant increase in the activities of Aspartate transaminae (AST), Alanine transaminase (ALT), Alkaline phosphatase (ALP), Gamma glutamyl transferase (GGT), Total Bilirubin, Cholesterol, Triglycerides, Lipid peroxide (LPO) also decreased the levels of Total protein, Glycogen, Superoxide dismutase (SOD) and Reduced glutathione (GSH). The oral administration of Indigofera linnaei Ali (100 mg/kg bw) along with carbon tetrachloride for 21 days reversed these altered parameters to normal level which indicating the hepatoprotective efficacy of Indigofera linnaei Ali against carbon tetrachloride induced liver injury.