EVALUATING COMPLICATIONS AND QUALITY OF LIFE OF DIALYSIS IN DIABETES MELLITUS

Abstract

Background: Diabetes is a metabolic disease that affects many organ systems and is one of the most common ones
affecting people worldwide. One of the leading causes of end-stage renal disease (ESRD) worldwide is diabetes.
Aim: The purpose of this study was to evaluate the results of managing diabetes with dialysis in comparison to people
without the disease.
Methods: During a 14-month period, 266 hemodialysis maintenance participants were prospectively examined for the
study. Hospitalization, cause of death, and hemodialysis departure were evaluated in each of the included participants
and compared to non-diabetic subjects.
Results: Of 266 patients, 40.97% (n=109) had a history of diabetes. Compared to non-diabetic participants, diabetic
subjects had significantly worse SF36 scores, high serum triglycerides and LDL cholesterol, lower iPTH, low serum
albumin, high CRP, greater cardiovascular morbidities, shorter dialysis durations, and older ages. Diabetics had a 1.9-
fold increased risk of death from disease than non-diabetics. Infection and other causes of cardiovascular disease
accounted for 54% of deaths in non-diabetics and 80% of deaths in diabetics. Diabetics also had a much higher annual
admission rate.
Conclusions: The current study finds that, in comparison to non-diabetic participants receiving hemodialysis, diabetic
people had significantly worse clinical outcomes and HRQOL (health-related quality of life). This difference is mostly
attributable to the increased frequency of cardiovascular illnesses.