PREVALENCE OF DRUG-INDUCED NEPHRITIS IN NORTH-EAST INDIAN POPULATION

Abstract

Background: Drug-induced renal illness is one of the most frequent etiological causes contributing to acute renal failure
and chronic kidney disease in the current clinical setting. Different medicines cause certain typical renal responses by direct
toxicity and immunologic mechanism virtue.
Aim: The purpose of this study was to evaluate drug-induced nephrotoxicity incidence and prevalence in north east
population.
Methods: 500 participants in a predetermined age group were selected for the study, and anthropometric and demographic
data were collected. Serum creatinine was then measured, and protein was analyzed using the dipstick method. The 4-
variable modification of diet in renal disease (MDRD) equation and the Cockcroft-Gault equation adjusted for body surface
area (CG-BSA) were used to estimate the glomerular filtration rate (eGFR).