EVALUATION OF PRE-INVASIVE LESIONS ASSOCIATED WITH CERVICAL CARCINOMA USING A VARIETY OF SCREENING METHODS- A COMPARATIVE STUDY

Abstract

Background: Cancer screening is easy to do and may be done in pre-invasive stages, which enables surgery or chemoradiotherapy to treat these lesions in a conservative and efficient manner.

Aim: Examining the various methods for detecting and screening pre-invasive lesions of cervical cancer, such as colposcopy, pap smear, visual cervix examination with iodine and acetic acid, and visual cervix examination with Lugol's iodine, was the aim of the current study.

Methods: After obtaining a medical history, eighty females ranging in age from twenty to sixty underwent a pap smear, acetic acid, Lugol's iodine cervix inspection, and colposcope. After the collected data were statistically analysed, conclusions were drawn with a significance level of 0.05. 

Results: According to Lugol's iodine and acetic acid with a visual examination, pap smear, and colposcopy, only 2.5% (n=2) of the subjects had a cervix free of abnormalities, while 56.25% (n=45) of the female subjects had cervicitis, 22.5% (n=18) of the subjects had Intraepithelial carcinoma-1, 16.25% (n=13) of the subjects had Intraepithelial carcinoma-2/3, and 2 (2.5%) of the subjects had microinvasive carcinoma that was confirmed.

Conclusion: The study concludes that the combination of pap smear cytology, ocular inspection, and colposcopy enhances the probability of detecting invasive and pre-invasive lesions.