MAPPING THE LEVELS OF CREATININE, UREA AND BETA HCG IN VAGINAL FLUIDS

Abstract

Background: Creatinine and urea are used in the diagnosis of premature miscarriage (PROM) since urine excretion
in amniotic fluid begins during the eighth and tenth gestational week. Beta-human chorionic gonadotropin, or B-hCG,
is released by syncytiotrophoblast and found in mother's blood and amniotic fluid. Its evolutionary significance is
being investigated.
Aim: In order to detect premature rupture of the membranes, or PROM, the current study set out to map the levels of
creatinine, urea, and beta-human growth hormone in vaginal secretions.
Methods: The study evaluated women who were split into two groups. Group I included pregnant women in the 28–
40 week gestational age range who had a history of leaking vagina without the commencement of labour pain and a
clinical diagnosis of PROM. Group II consisted of control pregnant women with no PROM who were between the
ages of 28 and 40 weeks. The amounts of creatinine, urea, and beta-hCG in the vaginal fluids of these two groups
were compared.