ANTIFUNGAL POTENTIAL OF DIFFERENT EXTRACTS OF SYZYGIUM AROMATICUM AGAINST MICROSPORUM GYPSEUM

Abstract

Present research was carried out to evaluate the effectiveness of different extracts of Syzygium aromaticum in the treatment of multifarious dermal infections caused by Microsporum gypseum. The present work was conducted to find out the antifungal potential of various extracts of dried powder of buds of Syzygium aromaticumby means of paper disc diffusion method, with petroleum ether, ethyl acetate, ethanol, and aqueous solvents in 25 µml, 50 µml and 100 µml concentrations against Microsporum gypseum. Clotrimazole, a synthetic antifungal drug was used as a standard. The present study revealed that Syzygium aromaticum is a potent antifungal agent against Microsporum gypseum. The ethanol extract of Syzygium aromaticum using 100 µml concentrations depicted the highest zone of inhibition of 19.690+ 0.86 mm and 45.790 % of mycelial inhibition against a tested pathogen.