PHYTOCHEMICAL EVALUATION AND IN-VITRO ANTIOXIDANT POTENTIAL OF WHOLE PLANT OF TANACETUM PARTHENIUM (L)

Abstract

In the current scenario, exploration is aimed at scrutinizing the phytochemicals for total phenol content, total Flavonoid estimation, antioxidant potentials obtained from natural origin. The study was focused on evaluation of antioxidant potential of various extracts of Tanacetum parthenium whole plant based on polarity. The total phenolic content and flavonoid content of Ethanolic extract of plant was found to be 32.91 ± 0.629 mg and 67.55 ± 1.170 mg of GAE and Quercetin equivalents respectively. Different in-vitro assays such as 2-2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method, Nitric oxide scavenging activity and reducing power estimation were studied for the various plant extracts and measured spectroscopically. The Ethanolic extract of plant showed the highest antioxidant activity as measured by DPPH, nitric oxide scavenging activity with IC50 values of 197.543 ± 0.659 and 266.449 ± 0.761 respectively. A strong correlation was observed between antioxidant capacities and their total phenolic content indicated that phenolic compounds were a major contributor to antioxidant properties of plant extract. These results suggest that the Ethanolic extract of Tanacetum parthenium can constitute a promising new source of natural compounds with antioxidants ability.