REVIEW ON SUBSTITUTED 1,3,4-OXADIAZOLE AND ITS BIOLOGICAL ACTIVITIES

Abstract

Oxadiazole or furadiazole is a five membered heterocyclic nucleus and is considered to be derived from furan by replacement of two methane (-CH=) group by pyridine type nitrogen. Oxadiazole is a versatile lead compound for designing potent bioactive agents. The derivative of oxadiazole nuclei (1,3,4-oxadiazole) showed diverse biological activities such as anti-microbial, anti-inflammatory, anti-tubercular, anti-convulsant, anti-cancer, anti- HIV, hypoglycemic and genotoxic. In this article, we have tried to compile some of the major researches carried out for the compound 1,3,4- oxadiazole.