OVERVIEW ON RECENT EXTRACTION TECHNIQUES IN BIOANALYSIS

Abstract

This review is focused on Bioanalytical Strategies and gives update on the Bioanalytical Tools in Drug Discovery. The method used for sample collection, sample preparation. In sample preparation liquid-liquid extraction [LLE], solid phase extraction [SPE] and protein precipitation is traditional method. The recent methods are salting out assisted liquid extraction, protein precipitation plate and development in solid phase extraction in that molecularly imprinted polymer SPE, dispersive SPE, disposable pipette extraction, micro extraction by packed solvent, solid phase micro extraction, stir bar Sportive extraction and on line solid phase extraction ,this developed Bioanalytical methods applied various purposes such as pharmacokinetic studies, pharmacodynamic studies and comparative clinical studies.