EVALUATION OF INTUBATING STATE USING TRAIN OF FOUR STIMULATION WITH 0.6 MG/KG ROCURONIUM IN SUBJECTS UNDERGOING ELECTIVE SURGERIES

Abstract

Background: With the neuromuscular blocking agents, it is recommended to use TO (train of four) stimulation. The
assessment of intubating state using train of four and 0.6mg/kg rocuronium is scarce in the literature. Aims: The present
study was done for estimation of the subject's proportion with an excellent intubating state with the use of
0.6mg/kgrocuronium and train of four at adductor pollicislongus at different time intervals, immediately and 24 hours
after extubation, time to reach T0 and T1 and time to attain sore throat. Methods: 212 subjects were divided into 2 groups
namely T0 and T1 where the intubating state was evaluated following 0.6mg/kg rocuronium and monitoring by the train
of four. The data collected were statistically analyzed with a t-test and Chi-square test where p<0.05 was taken as the
level of statistical significance. Results: Intubating time was 132.58±30.73 seconds which was 142.96±27.06 seconds for
Group T0 and 122.36±30.78 seconds for T1 which was significantly higher for T0 with p<0.01. Intubating condition was
poor in 0.92% (n=1), good in 5.55% (n=6), and excellent in 93.51% (n=101) subjects respectively of group T0, whereas,
in Group T1, it was poor, good, and excellent in 1.92% (n=2), 8.65% (n=9), and 89.42% (n=93) subjects respectively.
Conclusion: Non-significantly higher proportion of subjects with excellent intubating conditions were seen at T0 after
0.6mg/kg rocuronium administration. 20 seconds more were taken to reach T0 compared to T1with less immediate and
late sore throat incidence.