EVALUATION OF PROTECTIVE ROLE OF QUERCETIN ON PACLITAXEL-INDUCED LIPID PEROXIDATION

Abstract

The objective of the present study was to explain antiperoxidative potential of quercetin on paclitaxel-induced lipid peroxidation. Goat liver was used as lipid source. This in vitro work was carried out by measuring using malondialdehyde and 4-hydroxy-2-nonenal content as model markers. The findings suggest that paclitaxel could induce lipid peroxidation to a significant extent and it was also found that quercetin has the ability to suppress the paclitaxel-induced toxicity.