MICROWAVE ASSISTED SYNTHESIS OF 2-AMINO-3,4,5-TRISUBSTITUTED IMIDAZOLINES USING RADISZEWSKI METHOD, THEIR CHARACTERISATION AND EVALUATION FOR ANTIOXIDANT ACTIVITY

Abstract

A facile synthesis of series of 2-amino-3,4,5-triphenyl-1H-imidazole was carried out. In the present research work, with the help of microwave irradi- ations the above said compounds were synthesised and also wherever necessary their synthesis was assisted by the use of catalyst. The method pos- sessed remarkable advantages, such as short reaction time and moderate to excellent yield. Microwaves provide environment friendly reactions by the use of lesser expensive polar solvents. Finally, all synthesised compounds were evaluated for antioxidant activity by reducing power method and DPPH free radical scavenging assay method.