NON AQUEOUS MICROEMULSIONS: NOVEL APPROACH FOR DELIVERY OF POORLY SOLUBLE DRUGS

Abstract

Non Aqueous microemulsion have attracted a great deal of attention not only because of there importance in industrial application but also there intrinsic interest. They optimize the performance of a wide spectrum of products and processes. Non Aqueous microemulsions are suitable for poorly aqueous soluble drugs and thermodynamically stable multicomponent fluids composed of polar solvent, oil and mixture of a. Liquid administration of drugs is one of the convient and often-advantageous delivery, especially when dealing with children or the elderly for whom pill swallowing can be difficult or even hazardous. Unfortunately many drugs are not soluble in water, while water solution of it may have an unpleasant taste. Some drugs are either unstable in the presence of water or are insoluble in water and therefore cannot be incorporated into aqueous formulations. To overcome these various problems a water free liquid preparation of a number of drugs would be desirable.