EVALUATING THE RELATIONSHIP BETWEEN GLYOXALASE 1 AND BLOOD LEVELS OF MAGNESIUM, MANGANESE, AND SELENIUM IN INDIVIDUALS WITH DIABETES MELLITUS

Abstract

Background: First of all, Glyoxalase-1 is an erythrocyte enzyme that is part of the glyoxalase system and aids in the catabolization of methylglyoxal. Additionally, AGEs (advanced glycation end products) are precursors to this enzyme. Glyoxalase levels affect the development of diabetes problems caused by elevated AGE and methylglyoxal levels. There is little information on the relationship between trace elements and glyoxalase-1 in diabetics.