ANTIBACTERIAL, ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITIES OF THE HYDROALCOHOLIC EXTRACT OF THE LEBANESE PLANT: EPHEDRA CAMPYLOPODA
Keywords:
Ephedra campylopoda,, phytochemical screening, antioxidant activity,, antiproliferative activity,Abstract
In order to determine the chemical composition of the hydroalcoholic extract obtained from the stems of the Lebanese plant Ephedra campylopoda, a phytochemical screening was carried out. The latter aids in identifying the content of this extract in primary and secondary metabolites in order to study and for the first time, some of the biological activities (as the antioxidant, antiproliferative and antibacterial) of this plant. The obtained results showed that the stems of Ephedra campylopoda are rich in several bioactive molecules such as polyphenols, flavonoids, tannins, etc. This wealth presented a remarkable antioxidant activity at a concentration of 0.5 mg/mL. It also presented an antiproliferative effect on two types of cancer cells: epithelial HT-29 and human colon HCT-116. Finally, its antibacterial effect was noticed against five bacterial strains. The obtained results encourage further research to be conducted in order to confirm the antibacterial, antioxidant and antiproliferative effects of this Lebanese plant.
