SYNTHESIS AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF 1- BENZOYL-1H-PYRAZOLO [4,3-C]QUINOLIN-4(5H)-ONES

Authors

  • Shivashankar Murugesh
  • Mandal Badal Kumar
  • Arul prakash G

Keywords:

4-Dichloroquinolines, 2, 4-chloro-3-formylquinolin-2-[1H] ones, Pyrazolo quinolone, antimicrobial activity

Abstract

A series of 1-benzoyl-1H-pyrazolo [4,3-C]quinolin-4(5H)-one, carrying appropriate substituents at the Quinoline ring have been synthesized in good yields via the condensation of 4-chloro-3-formylquinolin- 2[1H]ones with benzohydrazide using triethylamine as a base. All the synthesized compounds were evaluated for their antibacterial activities.

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Published

23-01-2011

Issue

Volume 2, Issue 1 January 2011

Section

Articles