FORMULATION AND EVALUATION OF ANTIAGING CREAM CONTAINING MANGIFERIN

Abstract

Skin aging can be described as irregular pigmentation, increased wrinkling, loss of elasticity, dryness and roughness. Phaleria macrocarpa is known as Mahkota Dewa in Malay and commonly available in Malaysia. The fruits contain large quantity of mangiferin which possess medicinal benefits including anti-diabetic, antioxidant, anti-proliferative, immunodulatory, cardiotonic and diuretic properties. However, there is no formulation has been developed though it was reported for many biological properties. The aim of our study is to formulate and evaluate anti-aging cream containing mangiferin as an active ingredient. Two formulations with different concentrations of mangiferin were formulated by mixing oil and aqueous phase using homogenizer. Both the formulations showed significant antioxidant activity and tyrosinase inhibition. The formulated creams were consistent in quality and safe to be used on the skin. These results demonstrate that mangiferin isolated from P. macrocarpa has a good potential for cosmetic product development.