EVALUATION OF EFFECT OF HYDROALCOHOLIC EXTRACT OF CASSIA FISTULA LINN AGAINST NEUROPATHIC PAIN

Abstract

Cassia fistula is widely grown as an ornamental plant in tropical and subtropical areas. Hydroalcoholic extract of Cassia fistula Linn leaf were assayed in wistar, strain albino rats. The extracts were found to possess significant neuropathy activity. In the present investigation, the rats were exposed to alcohol & acrylamide induced peripheral neuropathy in dose dependent manner. Cassia fistula leaf was unable to protect the animals from acrylamide while it was able to reverse the alcohol induced peripheral neuropathy in dose dependent manner in the rats. The results suggest that Cassia fistula could be of immense importance in the amelioration of the mono neuropathy in the human beings.