ANTIFUNGAL ACTIVITY OF MULTIPURPOSE CONTACT LENS SOLUTIONS AGAINST CANDIDA ALBICANS

Abstract

Multipurpose contact lens solution / MPS (multipurpose solution) is a contact lens disinfecting solution to disable microbes that can cause infections in the eyes. The cause of the infection is the lessened activity of the multipurpose solution on the contact lens. The research aims to determine the antifungal activity of the multipurpose solution against Candida albicans and determine the time contact of the multipurpose solutions. This study evaluated the antifungal activity of five MPSs that were tested based on based on the International Organization for Standardization (ISO) 14729, with time contacts of 1,3,6 and 12 hours. The results showed that MPS has antimicrobial activity against Candida albicans with a contact time of 3 hours. MPS containing polyhexanide as the active agent was found to have excellent antifungal activity and a desirable contact time.