ESTIMATION OF GEMCITABINE-INDUCED LIPID PEROXIDATION USING COMMON LABORATORY MARKERS: ROLE OF MORIN

Abstract

The objective of the present in vitro study was to explore antiperoxidative potential of morin on gemcitabine-induced lipid peroxidation. Goat liver tissue homogenate was used as source of lipid. Two common laboratory markers such as malondialdehyde and reduced glutathione were used for the model. The results showed that gemcitabine has the ability to induce lipid peroxidation to a significant extent and it was also found that morin has the ability to suppress the gemcitabine-induced toxicity.