IN VITRO FERTILIZATION

Abstract

First written document dealing with infertility may be found in the Kahoun papyrus (oldest Egyptian medical text), dated to 2200-1950 BC. The early attribution of infertility to women persisted for centuries and was often considered divine punishment.

Infertility means 1 year of well-timed, unprotected intercourse without a pregnancy. The study shows about 10-15% of population is infertile. And 15-20% of couple have unexplained infertility (work-up is negative). Normally women are born with their lifetime egg supply, the Fertility initially declines at age 27.Significant decline at age 37-38. The chances of pregnancies are rare after age 44 besides this defect in female ovary, fallopian tube, uterus, and fibroid tumour causes infertility in female.

Abnormality in sperm production and abnormality in sperm function causes infertility in male.

To overcome the infertility egg are harvested from womens ovary and fertilized in laboratory with the sperm the embryos are then transfer into uterus known as In Vitro Fertilization.